Miami Airport, December 7, 2005: a jet passenger begins yelling about a bomb threat and bolts for the door. Refusing to comply with two U.S. marshals, he is eventually shot to death. The cause of his outburst—bipolar disorder, not terrorism—comes to light soon after, proffering another tragic example of how volatile and misunderstood the disease is. This program examines the lives of people who have struggled for decades with bipolar disorder, once known as manic depression. Through case studies and discussions of recent research, the film shows how each patient has overcome the grip of debilitating despair and hyperactive euphoria, and how advances in psychology and neuroscience are helping such individuals lead better, more productive lives. (45 minutes)